I le pharmacology, intermediates o mea faʻapipiʻi faʻapipiʻiina mai mea faʻapipiʻi faigofie, e masani ona faʻaaogaina i le faʻasologa mulimuli ane o oloa e sili atu ona faigata, e pei o vailaʻau faʻamalosi malosi (APIs).
E taua tele i le atina'eina o vaila'au ma le gaosiga o vaila'au aua latou te fa'afaigofieina gaioiga fa'ama'i, fa'aitiitia tau, po'o le fa'ateleina o fua o vaila'au. E ono leai se a'afiaga o vaila'au fa'agata pe ono o'ona ma o lea e le talafeagai ai mo le taumafaina e tagata.
Intermediates e fausia i le taimi o le tuʻufaʻatasia o mea mataʻutia ma o mea ia e iai aʻafiaga faʻapitoa i vailaʻau. APIs o vaega autu ia o vailaʻau ma fuafua le lelei, saogalemu ma le aoga o vailaʻau. APIs e masani ona tu'ufa'atasia mai mea mata'utia po'o puna'oa fa'alenatura ma fa'ata'ita'iina ma fa'amaonia fa'amalosi a'o le'i fa'aogaina mo taumafa a tagata.
O le eseesega tele i le va o intermediates ma API o mea vavalo o mea muamua ia e saofagā i le gaosiga o API, aʻo API o mea malosi ia e sao saʻo i aʻafiaga o vailaʻau. O faʻatulagaga ma galuega a tagata vavalalata e sili atu ona faigofie ma faʻaitiitia le faʻamalamalamaina, aʻo vailaʻau vailaʻau e faʻalavelave ma faʻapitoa faʻalapotopotoga ma gaioiga. E itiiti ni mana'oga fa'aletulafono ma fa'amautinoaga lelei, ae o API o lo'o fa'atatau i tulaga fa'atulafonoina ma le fa'atonutonu lelei.
O lo'o fa'aaogaina lautele i vaega eseese ma alamanuia e pei o vaila'au lelei, biotechnology, ma vaila'au fa'ato'aga. O loʻo faʻaauau pea ona atinaʻe ma faʻalauteleina faʻatasi ma le tulaʻi mai o ituaiga fou ma ituaiga fou o fesoʻotaʻiga, e pei o chiral intermediates, peptide intermediates, ma isi.
Intermediates o le ivi pito i tua o vailaau faʻaonaponei ona e mafai ai ona faʻapipiʻiina ma gaosia API ma vailaʻau. Intermediates o ki i le faʻafaigofieina, faʻavasegaina ma faʻafouga i le vailaʻau faʻafomaʻi, e maua ai le lelei o vailaʻau ma le faʻatinoga.
Taimi meli: Feb-28-2024